Chromatin modifications, epigenetics, and how protozoan parasites regulate their lives
نویسندگان
چکیده
منابع مشابه
Topical Review on Epigenetics and Chromatin Modifications Epigenetics: Beyond Chromatin Modifications and Complex Genetic Regulation
Chromatin modifications and epigenetics may play important roles in many plant processes, including developmental regulation, responses to environmental stimuli, and local adaptation. Chromatin modifications describe biochemical changes to chromatin state, such as alterations in the specific type or placement of histones, modifications of DNA or histones, or changes in the specific proteins or ...
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Posttranslational modifications to histones affect chromatin structure and function resulting in altered gene expression and changes in cell behavior. Aberrant gene expression and altered epigenomic patterns are major features of cancer. Epigenetic changes including histone acetylation, histone methylation, and DNA methylation are now thought to play important roles in the onset and progression...
متن کاملChromatin Modifications and Their Function
The surface of nucleosomes is studded with a multiplicity of modifications. At least eight different classes have been characterized to date and many different sites have been identified for each class. Operationally, modifications function either by disrupting chromatin contacts or by affecting the recruitment of nonhistone proteins to chromatin. Their presence on histones can dictate the high...
متن کاملEpigenetics: Beyond Chromatin Modifications and Complex Genetic Regulation.
Chromatin modifications and epigenetics may play important roles in many plant processes, including developmental regulation, responses to environmental stimuli, and local adaptation. Chromatin modifications describe biochemical changes to chromatin state, such as alterations in the specific type or placement of histones, modifications of DNA or histones, or changes in the specific proteins or ...
متن کاملProtozoan Parasites
When viewed from the top, Trichodina is circular; side views of the organism reveal a saucer or dome shape (Fig. 1). It has three rings of cilia (small, hair-like projections) encircling its body and oral cavity, which are used for locomotion and feeding. Its body is supported by a rigid ring of interconnected discs called a chitinoid or denticular ring (Fig. 2). Each disc has a thorn-like inne...
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ژورنال
عنوان ژورنال: Trends in Parasitology
سال: 2012
ISSN: 1471-4922
DOI: 10.1016/j.pt.2012.02.009